BDBM5138 5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-5-ylidene]methyl}-N-[2-(diethylamino)ethyl]-4-methyl-1H-pyrrole-2-carboxamide::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26p

SMILES CCN(CC)CCNC(=O)c1cc(C)c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)[nH]1

InChI Key InChIKey=SXQLWNOERMLQGM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5138   

LigandPNGBDBM5138(5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...)
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2005
Entry Details Article
PubMed
LigandPNGBDBM5138(5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...)
Affinity DataIC50: 1.20nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2005
Entry Details Article
PubMed
LigandPNGBDBM5138(5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...)
Affinity DataIC50: 2.00E+4nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2005
Entry Details Article
PubMed