BDBM513694 US11091495, Example 55::US11220509, Example 55::US11485738, Example 55::US20240398811, Example 55

SMILES Fc1ccc2OCCc2c1CNc1ncc(-c2ccc(CN3CCC(F)(F)C3)cc2)c2nc(cn12)C#N

InChI Key InChIKey=OSVFUMKEOIGMJL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 513694   

LigandPNGBDBM513694(US11220509, Example 55 | US11091495, Example 55 | ...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent

LigandPNGBDBM513694(US11220509, Example 55 | US11091495, Example 55 | ...)
Affinity DataIC50: 100nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
Go to US Patent

LigandPNGBDBM513694(US11220509, Example 55 | US11091495, Example 55 | ...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM513694(US11220509, Example 55 | US11091495, Example 55 | ...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present disclosure were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent