BDBM513650 5-(((5-fluorobenzofuran-4-yl)methyl)amino)-8-(2-methylpyridin-3-yl)imidazo[1,2-c]pyrimidine-2-carboxamide::US11091495, Example 12

SMILES Cc1ncccc1-c1cnc(NCc2c(F)ccc3occc23)n2cc(nc12)C(N)=O

InChI Key InChIKey=SMHLMPSZVTVQDP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 513650   

LigandPNGBDBM513650(5-(((5-fluorobenzofuran-4-yl)methyl)amino)-8-(2-me...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
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LigandPNGBDBM513650(5-(((5-fluorobenzofuran-4-yl)methyl)amino)-8-(2-me...)
Affinity DataIC50: 100nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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LigandPNGBDBM513650(5-(((5-fluorobenzofuran-4-yl)methyl)amino)-8-(2-me...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent