BDBM513640 5-(((5-fluorobenzofuran-4-yl)methyl)amino)-8-(2-methylpyridin-3-yl)imidazo[1,2-c]pyrimidine-2-carboxylic acid::US11091495, Example 3::US11220509, Example 12::US11485738, Example 3::US20240398811, Example 3

SMILES Cc1ncccc1-c1cnc(NCc2c(F)ccc3occc23)n2cc(nc12)C(O)=O

InChI Key InChIKey=SSPXUFXDBGMUJX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 513640   

LigandPNGBDBM513640(US11220509, Example 12 | 5-(((5-fluorobenzofuran-4...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
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LigandPNGBDBM513640(US11220509, Example 12 | 5-(((5-fluorobenzofuran-4...)
Affinity DataIC50: 300nMAssay Description:An aliquot of each serial dilution of test compound was added to deep 384 well plate using Acoustic Technology instrument (Echo 550, LabCyte) contain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
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LigandPNGBDBM513640(US11220509, Example 12 | 5-(((5-fluorobenzofuran-4...)
Affinity DataIC50: 500nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM513640(US11220509, Example 12 | 5-(((5-fluorobenzofuran-4...)
Affinity DataIC50: 100nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

LigandPNGBDBM513640(US11220509, Example 12 | 5-(((5-fluorobenzofuran-4...)
Affinity DataIC50: 300nMAssay Description:Briefly, compounds of the present disclosure were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent