BDBM5136 (5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-methyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylidene)-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 26n

SMILES CN1CCN(CC1)C(=O)c1c[nH]c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)c1C

InChI Key InChIKey=UYSSUZUSGKWSFS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5136   

LigandPNGBDBM5136((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-meth...)
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2005
Entry Details Article
PubMed
LigandPNGBDBM5136((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-meth...)
Affinity DataIC50: 410nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2005
Entry Details Article
PubMed
LigandPNGBDBM5136((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-meth...)
Affinity DataIC50: 2.00E+4nMAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2005
Entry Details Article
PubMed