BDBM513512 US11091482, Compound I-59

SMILES Cc1cc(cc2sc(nc12)N1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1c(noc1C1(F)CC1)-c1c(Cl)cccc1Cl)C(O)=O

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 513512   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM513512(US11091482, Compound I-59)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent