BDBM513511 US11091482, Compound I-58

SMILES COC12CCC(CC1)(CC2)c1noc(C2CC2)c1C(=O)O[C@@H]1C[C@@H]2CC[C@H](C1)N2c1nc2c(OC(F)(F)F)cc(cc2s1)C(O)=O

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 513511   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM513511(US11091482, Compound I-58)
Affinity DataEC50: <3.98E+4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent