BDBM513510 US11091482, Compound I-57

SMILES OC(=O)c1cc(OC(F)(F)F)c2nc(sc2c1)N1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1c(onc1C12CCC(CC1)CC2)C1CC1

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 513510   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM513510(US11091482, Compound I-57)
Affinity DataEC50:  1.00E+3nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
Go to US Patent