BDBM512393 Preparation of 1-(4-methyl-3-((1-methyl-6-((1,2,3,4-tetrahydroisoquinoline-7-yl)amino)-1H-pyrazolo[3,4-d]pyrimidine-3-yl)amino)phenyl)-3-(3-(trifluoromethyl)phenyl)urea::US11084824, Example 57

SMILES Cc1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1Nc1nn(C)c2nc(Nc3ccc4CCNCc4c3)ncc12

InChI Key InChIKey=GIAMOPWGDZUOFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 512393   

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512393(Preparation of 1-(4-methyl-3-((1-methyl-6-((1,2,3,...)
Affinity DataIC50: 26.7nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
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Date in BDB:
1/24/2022
Entry Details
US Patent