BDBM512360 Preparation of N3-(2,6-dichlorophenyl)-1-methyl-N6-(1,2,3,4-tetrahydroisoquinoline-6-yl)-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine::US11084824, Example 15

SMILES Cn1nc(Nc2c(Cl)cccc2Cl)c2cnc(Nc3ccc4CNCCc4c3)nc12

InChI Key InChIKey=DCIMEFIVIWONCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 512360   

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512360(Preparation of N3-(2,6-dichlorophenyl)-1-methyl-N6...)
Affinity DataIC50: 0.670nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
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Date in BDB:
1/24/2022
Entry Details
US Patent