BDBM5118 US8530490, 397::US8530490, 49::US8530490, 6

SMILES C[C@@H](NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1cccc(OC2CCOC2)c1

InChI Key InChIKey=PYEMJJWRUPXOOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5118   

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM5118(US8530490, 6 | US8530490, 49 | US8530490, 397)
Affinity DataIC50: 460nMAssay Description:The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2013
Entry Details
Go to US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM5118(US8530490, 6 | US8530490, 49 | US8530490, 397)
Affinity DataIC50: 940nMAssay Description:The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2013
Entry Details
Go to US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM5118(US8530490, 6 | US8530490, 49 | US8530490, 397)
Affinity DataIC50: 460nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
Go to US Patent