BDBM511749 1-(2-((1R,3S,5R)-3-((6-bromo-3- methylpyridin-2-yl)carbamoyl)-5-methyl-2- azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)-7- methyl-5-(2-methylpyrimidin::US11084800, Cpd No. 57::US11708351, Compound 57

SMILES Cc1ncc(cn1)-c1cc(C)c2n(CC(=O)N3[C@@H]4C[C@]4(C)C[C@H]3C(=O)Nc3nc(Br)ccc3C)nc(C(N)=O)c2c1

InChI Key InChIKey=IMLCRNUHDGYXGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511749   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511749(US11084800, Cpd No. 57 | 1-(2-((1R,3S,5R)-3-((6-br...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511749(US11084800, Cpd No. 57 | 1-(2-((1R,3S,5R)-3-((6-br...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent