BDBM511726 (3S)-2-(2-(3-acetyl-7-(methoxymethyl)-5-(2- methylpyrimidin-5-yl)-1H-indazol-1- yl)acetyl)-N-(6-bromopyridin-2- (methoxymethyl)-2-azabicyclo[3.1.0]hexane- 3-carboxamide::US11084800, Cpd No. 32::US11708351, Compound 32

SMILES COCc1cc(cc2c(nn(CC(=O)N3C4CC4(COC)C[C@H]3C(=O)Nc3cccc(Br)n3)c12)C(C)=O)-c1cnc(C)nc1

InChI Key InChIKey=GMJFFYJSOHDDFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511726   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511726(US11084800, Cpd No. 32 | (3S)-2-(2-(3-acetyl-7-(me...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511726(US11084800, Cpd No. 32 | (3S)-2-(2-(3-acetyl-7-(me...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent