BDBM511494 US11059792, Compound T8

SMILES C[C@H]1[C@@H]2CCc3c(nc(-c4ccccc4)n3-c3nnn(C)n3)[C@@]2(C)C=C(C#N)C1=O

InChI Key InChIKey=TVBPUXGHUSYBHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 511494   

TargetNitric oxide synthase, inducible(Human)
Reata Pharmaceuticals

US Patent
LigandPNGBDBM511494(US11059792, Compound T8)
Affinity DataIC50: 28.8nMAssay Description:RAW 264.7 cells were plated 1 day in advance of experiment at a concentration of 80,000 cells/well onto CellBIND 96 well plates (Corning, N.Y.) in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
Go to US Patent