BDBM511225 2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-3-ethynyl-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)-2-(4-(3-methyl-2-oxotetrahydropyrimidin-1 (2H)-yl)benzyl)malonic acid::US11078228, Example 149

SMILES CN1CCCN(C1=O)c1ccc(CC(OC[C@H]2O[C@H]([C@H](O)[C@@]2(O)C#C)n2cnc3c(N)nc(Cl)nc23)(C(O)=O)C(O)=O)cc1

InChI Key InChIKey=YFAHLSUKGIJHPE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 511225   

Target5'-nucleotidase(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM511225(2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-y...)
Affinity DataIC50: 0.110nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
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Date in BDB:
1/16/2022
Entry Details
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