BDBM511066 US11078214, Compound PTX

SMILES CC(C)CC(NC(=O)N1CCN(Cc2nc[nH]c2C)C(=O)C1Cc1ccccc1)C(O)=O

InChI Key InChIKey=COLCNDRDBCLVOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511066   

TargetDihydrofolate reductase(Human)
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM511066(US11078214, Compound PTX)
Affinity DataIC50: 41nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM511066(US11078214, Compound PTX)
Affinity DataIC50: 2nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent