BDBM511063 US11078214, Compound 18

SMILES CN(c1ccc(OC(F)(F)F)cc1)c1ccc2nc(N)nc(C)c2n1

InChI Key InChIKey=MZGPHNVIRSJTRI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511063   

TargetDihydrofolate reductase(Human)
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM511063(US11078214, Compound 18)
Affinity DataIC50: 13nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM511063(US11078214, Compound 18)
Affinity DataIC50: 153nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent