BDBM511056 (Z)-7-((2R,3R,4S,5R)-5-((R)-(4- chlorophenyl)(hydroxy)methyl)-3,4- dihydroxy-4-methyltetrahydrofuran-2-yl)- 3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin- 4-one oxime::US11078205, Example 46::US11208416, Example 46

SMILES C[C@]1(O)[C@@H](O)[C@@H](O[C@@H]1[C@H](O)c1ccc(Cl)cc1)n1ccc2c1nc[nH]\c2=N/O

InChI Key InChIKey=WFXAZZULKQWXBX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511056   

TargetProtein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM511056((Z)-7-((2R,3R,4S,5R)-5-((R)-(4- chlorophenyl)(hydr...)
Affinity DataIC50: 92nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM511056((Z)-7-((2R,3R,4S,5R)-5-((R)-(4- chlorophenyl)(hydr...)
Affinity DataIC50: 92nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent