BDBM511051 US11078214, Compound 7

SMILES COc1ccc(Nc2ccc3nc(N)nc(C)c3n2)cc1

InChI Key InChIKey=JNUPSFKWAOWBMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511051   

TargetDihydrofolate reductase(Human)
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM511051(US11078214, Compound 7)
Affinity DataIC50: 239nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetDihydrofolate reductase(Human pneumocystis pneumonia agent)
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM511051(US11078214, Compound 7)
Affinity DataIC50: 1.10E+3nMAssay Description:These assays were carried out at 37° C. under 18 μM dihydrofolic acid concentration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent