BDBM510967 US11078197, Example 146::US11673886, Example 146

SMILES Cc1c(cnn1-c1ccc(cc1)C(F)(F)F)C(=O)N[C@H]1C[C@]2(C1)C[C@@H](C2)Oc1nc2n(C)ncc2cc1C(N)=O

InChI Key InChIKey=BUQATFKOFDAERV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510967   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510967(US11078197, Example 146 | US11673886, Example 146)
Affinity DataIC50: 5.20E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510967(US11078197, Example 146 | US11673886, Example 146)
Affinity DataIC50: 5.20nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2023
Entry Details
Go to US Patent