BDBM510892 1-cyclopropyl-3- ({(aR)-6-[7- cyclopropyl-6-(2- hydroxy-2- methylpropoxy)pyrazolo [1,5-a]pyridine- 3-amido]spiro[3.3] heptan-2-yl}oxy)-1H- pyrazole-4- carboxamide::US11078197, Example 69

SMILES CC(C)(O)COc1ccc2c(cnn2c1C1CC1)C(=O)N[C@H]1C[C@]2(C1)C[C@@H](C2)Oc1nn(cc1C(N)=O)C1CC1

InChI Key InChIKey=MGWLXISJMFSWFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510892   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510892(1-cyclopropyl-3- ({(aR)-6-[7- cyclopropyl-6-(2- hy...)
Affinity DataIC50: 4.50E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
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