BDBM510842 3-({(aR)-6-[7- cyclopropyl-6-(2- hydroxy-2- methylpropoxy)pyrazolo [1,5-a]pyridine-3- amido]spiro[3.3] heptan-2-yl}oxy)-1- ethyl-1H-pyrazole- 4-carboxamide::US11078197, Example 19

SMILES CCn1cc(C(N)=O)c(O[C@H]2C[C@@]3(C[C@@H](C3)NC(=O)c3cnn4c(C5CC5)c(OCC(C)(C)O)ccc34)C2)n1

InChI Key InChIKey=CTCAYWURIWFROB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510842   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510842(3-({(aR)-6-[7- cyclopropyl-6-(2- hydroxy-2- methyl...)
Affinity DataIC50: 1.05E+4nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent