BDBM510713 4-(2-((3S,4S)-3-(4-fluorophenyl)-4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-3-methylpyrrolidin-1-yl)-2-oxoethyl)benzamide::US11078186, Example 167

SMILES C[C@@]1(CN(C[C@H]1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)C(=O)Cc1ccc(cc1)C(N)=O)c1ccc(F)cc1

InChI Key InChIKey=ROHHNXAUNKHIFB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510713   

TargetNuclear receptor ROR-gamma [262-507](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510713(4-(2-((3S,4S)-3-(4-fluorophenyl)-4-(4-(1,1,1,3,3,3...)
Affinity DataIC50: 51nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent