BDBM510585 US11078186, Example 39::US11078186, Example 40

SMILES C[C@@]1(CN(C[C@H]1c1ccc(cc1)-c1c(F)cccc1F)C(=O)NCc1ccccc1)c1ccc(F)cc1

InChI Key InChIKey=DXSBPHKXGBSJGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510585   

TargetNuclear receptor ROR-gamma [262-507](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510585(US11078186, Example 40 | US11078186, Example 39)
Affinity DataIC50: 59nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetNuclear receptor ROR-gamma [262-507](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510585(US11078186, Example 40 | US11078186, Example 39)
Affinity DataIC50: 139nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent