BDBM510114 US11351149, Example 66::WO2021250648, Example 66

SMILES CC(C)C[C@H](NC(=O)c1cc2cccc(c2[nH]1)C(F)(F)F)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N

InChI Key InChIKey=GQTHPXZAMKDSPN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510114   

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM510114(WO2021250648, Example 66 | US11351149, Example 66)
Affinity DataIC50: 73nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021250648

TargetReplicase polyprotein 1a(2019-nCoV)
Pfizer

US Patent
LigandPNGBDBM510114(WO2021250648, Example 66 | US11351149, Example 66)
Affinity DataKi:  73nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
Go to US Patent