BDBM509991 Jun9-62-2R

SMILES C[C@H](NC(=O)[C@H](N(C(=O)C(Cl)Cl)c1ccc(cc1)-c1ccccc1)c1cccnc1)c1ccccc1

InChI Key InChIKey=LEOCNIZCHQOMFL-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 509991   

TargetReplicase polyprotein 1ab(2019-nCoV)
The University of Arizona

LigandPNGBDBM509991(Jun9-62-2R)
Affinity DataIC50: 430nMAssay Description:FRET-based enzymatic assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University of Arizona

LigandPNGBDBM509991(Jun9-62-2R)
Affinity DataIC50: 430nMAssay Description:Inhibition of SARS-CoV-2 main proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University of Arizona

LigandPNGBDBM509991(Jun9-62-2R)
Affinity DataIC50: 670nMAssay Description:Inhibition of SARS-CoV-2 main protease incubated for 30 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University of Arizona

LigandPNGBDBM509991(Jun9-62-2R)
Affinity DataIC50: 430nMAssay Description:Inhibition of recombinant N-terminal GST-tagged SARS-Cov-2 Main proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University of Arizona

LigandPNGBDBM509991(Jun9-62-2R)
Affinity DataIC50: 670nMAssay Description:Inhibition of SARS-CoV-2 3CL proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Huaqiao University

Curated by ChEMBL
LigandPNGBDBM509991(Jun9-62-2R)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Trypsin using Z-Phe-Arg-AMC as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCaspase-3(Human)
Huaqiao University

Curated by ChEMBL
LigandPNGBDBM509991(Jun9-62-2R)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human caspase 3 using Z-Phe-Arg-AMC as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Huaqiao University

Curated by ChEMBL
LigandPNGBDBM509991(Jun9-62-2R)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human calpain using Z-Phe-Arg-AMC as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed