BDBM508498 5-chloro-N-[(8S,9aR)-8-fluoro-5-oxo-8,9,9a,10-tetrahydro-5H,7H-pyrido[3,2-f]pyrrolo[2,1-c][1,4]oxazepin-3-yl]-2-methoxybenzenesulfonamide::US11046710, Example 44

SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cnc2OC[C@H]3C[C@H](F)CN3C(=O)c2c1

InChI Key InChIKey=BESIKZGWDMXHSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508498   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM508498(5-chloro-N-[(8S,9aR)-8-fluoro-5-oxo-8,9,9a,10-tetr...)
Affinity DataIC50: 0.800nMAssay Description:COS1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (Inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
Go to US Patent