BDBM507716 7-chloro-4-(methylamino)-1-phenyl- quinazolin-2(1H)-one::US11046691, Compound 2::US11084798, Cpd No 2

SMILES CNc1nc(=O)n(-c2ccccc2)c2cc(Cl)ccc12

InChI Key InChIKey=KTFNCXUTCFGSLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 507716   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM507716(US11046691, Compound 2 | 7-chloro-4-(methylamino)-...)
Affinity DataIC50: 200nMAssay Description:Materials:Enzyme: MAT2AhMAT2A: 50 nM, Cepter, 10 mg/mL (234 μM), amino acids 1-395Substrates: 500 uM eachReaction time: 1 hourL-methionine Subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent

TargetS-adenosylmethionine synthase isoform type-2(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM507716(US11046691, Compound 2 | 7-chloro-4-(methylamino)-...)
Affinity DataIC50: 200nMAssay Description:Enzyme: MAT2AhMAT2A: 50 nM, Cepter, 10 mg/mL (234 μM), amino acids 1-395Substrates: 500 uM eachReaction time: 1 hourL-methionine Substrate: Alfa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
Go to US Patent