BDBM507623 3-[[4-hydroxy-1-[(3R,4R)-3-phenyl-1-(2,2,2-trifluoroethyl)piperidine-4-carbonyl]-4-piperidyl]methyl]-7H-pyrrolo[2,3-d]pyrimidin-4-one::US11046681, Example 117

SMILES OC1(Cn2cnc3[nH]ccc3c2=O)CCN(CC1)C(=O)[C@@H]1CCN(CC(F)(F)F)C[C@H]1c1ccccc1

InChI Key InChIKey=QFHRCEAMGLYUCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 507623   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
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US Patent
LigandPNGBDBM507623(US11046681, Example 117 | 3-[[4-hydroxy-1-[(3R,4R)...)
Affinity DataIC50: 1.20E+3nMAssay Description:USP7 activity was measured using Rhodamine-110 c-terminal labelled Ubiquitin as a substrate (Viva Biosciences). Incubation with USP7 results in the r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
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