BDBM507547 US11046680, Example 441.0

SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(Cl)cn2)nnc1-c1noc2CCCCc12

InChI Key InChIKey=RZAFTNZDRNLYJA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 507547   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM507547(US11046680, Example 441.0)
Affinity DataEC50:  0.330nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent