BDBM507253 US11046680, Example 132.0

SMILES COc1ccc(cc1-n1c(NS(=O)(=O)CCc2ccc(F)cc2C#N)nnc1-c1cccs1)N1CCC1=O

InChI Key InChIKey=QJGIBFZLHXOMPP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 507253   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM507253(US11046680, Example 132.0)
Affinity DataEC50:  0.240nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent