BDBM50723 6-[(5E)-5-[[5-(4-chlorophenyl)-2-furanyl]methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]hexanoic acid::6-[(5E)-5-[[5-(4-chlorophenyl)-2-furyl]methylene]-4-keto-2-thioxo-thiazolidin-3-yl]hexanoic acid::6-[(5E)-5-[[5-(4-chlorophenyl)furan-2-yl]methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]hexanoic acid::6-[(5E)-5-[[5-(4-chlorophenyl)furan-2-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]hexanoic acid::6-{5-[1-[5-(4-Chloro-phenyl)-furan-2-yl]-meth-(E)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-hexanoic acid::MLS000777229::SMR000413624::US20230364057, Compound 36::cid_1901745

SMILES OC(=O)CCCCCN1C(=S)S\C(=C\c2ccc(o2)-c2ccc(Cl)cc2)C1=O

InChI Key InChIKey=HNIZZXVYVLSUHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50723   

LigandPNGBDBM50723(6-{5-[1-[5-(4-Chloro-phenyl)-furan-2-yl]-meth-(E)-...)
Affinity DataIC50: 1.27E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM50723(6-{5-[1-[5-(4-Chloro-phenyl)-furan-2-yl]-meth-(E)-...)
Affinity DataIC50: 7.42E+3nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent