BDBM506865 3-amino-6-(5-(3-amino- 1,1,1-trifluoro-2-hydroxy- 3-oxopropan-2-yl)-2- methylphenyl)-N-((S)-1- cyanobutan-2-yl)pyrazine- 2-carboxamide trifluoroacetate::US11046658, Example 20

SMILES CC[C@@H](CC#N)NC(=O)c1nc(cnc1N)-c1cc(ccc1C)C(O)(C(N)=O)C(F)(F)F

InChI Key InChIKey=OMXUPFQHXVNNFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 506865   

LigandPNGBDBM506865(3-amino-6-(5-(3-amino- 1,1,1-trifluoro-2-hydroxy- ...)
Affinity DataIC50: 100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
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LigandPNGBDBM506865(3-amino-6-(5-(3-amino- 1,1,1-trifluoro-2-hydroxy- ...)
Affinity DataIC50: 100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent