BDBM506860 3-amino-6-(5-(3-amino- 1,1,1-trifluoro-2-hydroxy- 3-oxopropan-2-yl)-2- methylphenyl)-N-(2-cyano- 2-methylpropyl)pyrazine-2- carboxamide trifluoroacetate::US11046658, Example 15

SMILES Cc1ccc(cc1-c1cnc(N)c(n1)C(=O)NCC(C)(C)C#N)C(O)(C(N)=O)C(F)(F)F

InChI Key InChIKey=UXSMSJFTJORPRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 506860   

LigandPNGBDBM506860(3-amino-6-(5-(3-amino- 1,1,1-trifluoro-2-hydroxy- ...)
Affinity DataIC50: 100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
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LigandPNGBDBM506860(3-amino-6-(5-(3-amino- 1,1,1-trifluoro-2-hydroxy- ...)
Affinity DataIC50: 100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
Go to US Patent