BDBM506846 US11046658, Example 1

SMILES Cc1ccc(cc1-c1cnc(N)c(n1)C(=O)NCC(C)(C)O)C(O)(C(N)=O)C(F)(F)F

InChI Key InChIKey=DVRSFYPTVOWAFS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 506846   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Incyte

US Patent

LigandBDBM506846(US11046658, Example 1)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/27/2021
Entry Details
Copy Entry DOIGo to US Patent

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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Incyte

US Patent

LigandBDBM506846(US11046658, Example 1)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/27/2021
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL