BDBM50669010 CHEMBL6192325

SMILES Cc1c(N2CCCC2=O)cccc1S(=O)(=O)N[C@@H](CNC(=O)c1ccc(Cl)s1)C(=O)OCCS(C)(=O)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50669010   

TargetCoagulation factor X(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 0.490nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetCoagulation factor X(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProthrombin(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProthrombin(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProthrombin(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProthrombin(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetCoagulation factor X(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetCoagulation factor X(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetProthrombin(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetTissue-type plasminogen activator(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetTrypsin(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 1.60E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetPlasma kallikrein(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 1.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetCoagulation factor XI(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 2.60E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetPlasminogen(Human)
Germany.F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50669010BDBM50669010(CHEMBL6192325)
Affinity DataIC50: 3.80E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed