BDBM50668854 CHEMBL6188533

SMILES O=C(Nc1ccc(CNC(=O)c2cc(F)ccc2N2CCCC2)cc1)OCc1cccnc1

InChI Key InChIKey=ULMUOHYPKGDIMQ-UHFFFAOYSA-N

Data  8 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50668854   

TargetNicotinamide phosphoribosyltransferase(Human)
University of South China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668854BDBM50668854(CHEMBL6188533)
Affinity DataIC50: 150nMAssay Description:Inhibition of N-terminal His-tagged human recombinant NAMPT expressed in Escherichia coli BL 21 (DE3) using NAM and PRPP as substrate preincubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of South China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668854BDBM50668854(CHEMBL6188533)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of South China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668854BDBM50668854(CHEMBL6188533)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of South China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668854BDBM50668854(CHEMBL6188533)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
University of South China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668854BDBM50668854(CHEMBL6188533)
Affinity DataKd:  5.01E+3nMAssay Description:Binding affinity to human recombinant NAMPT assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of South China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668854BDBM50668854(CHEMBL6188533)
Affinity DataIC50: 4.27E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of South China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668854BDBM50668854(CHEMBL6188533)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
University of South China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668854BDBM50668854(CHEMBL6188533)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of South China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668854BDBM50668854(CHEMBL6188533)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed