BDBM50668663 CHEMBL6192842

SMILES Cc1cc2c(c(O)c1-c1nnc(N[C@@H]3CCCC[C@H]3O)c3cnccc13)CCO2

InChI Key InChIKey=CAODOERBJCKNFB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50668663   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668663BDBM50668663(CHEMBL6192842)
Affinity DataIC50: 11nMAssay Description:Inhibition of NLRP3 in human whole blood assessed as decrease in IL-1beta level incubated for 3 hrs followed by nigericin stimulation for 1 hr by Alp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed