BDBM50668628 CHEMBL6189714

SMILES C[C@H](Oc1ccnc(-c2noc([C@@]3(C)CCCc4sc(N)c(C#N)c43)n2)n1)[C@@H]1CCCN1C

InChI Key InChIKey=MIUFORKWYHBPRW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50668628   

TargetGTPase KRas(Human)
Shengjing Hospital of China Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668628BDBM50668628(CHEMBL6189714)
Affinity DataIC50: 140nMAssay Description:Inhibition of KRAS G12D mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Shengjing Hospital of China Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668628BDBM50668628(CHEMBL6189714)
Affinity DataIC50: 140nMAssay Description:Inhibition of KRAS G12V mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Shengjing Hospital of China Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668628BDBM50668628(CHEMBL6189714)
Affinity DataIC50: 140nMAssay Description:Inhibition of KRAS G12C mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed