BDBM50667868 CHEMBL6190167

SMILES COc1ccc(C(=O)N2CCC(c3cc(-c4ccnc5[nH]ccc45)[nH]n3)CC2)cc1

InChI Key InChIKey=ZUJAIHLZMKLQOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50667868   

TargetRho-associated protein kinase 2(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667868BDBM50667868(CHEMBL6190167)
Affinity DataIC50: 492nMAssay Description:Inhibition of ROCK2 (unknown origin) incubated for 40 mins in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667868BDBM50667868(CHEMBL6190167)
Affinity DataIC50: 829nMAssay Description:Inhibition of ROCK1 (unknown origin) incubated for 40 mins in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed