BDBM50667838 CHEMBL6188577

SMILES CCN(c1cc(-c2ccc(CN3CCOCC3)cc2NC(=O)/C=C/COC)cc(C(=O)NCc2c(SC)cc(C)[nH]c2=O)c1C)C1CCOCC1

InChI Key InChIKey=OTLFBYAXRZIDPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50667838   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667838BDBM50667838(CHEMBL6188577)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed