BDBM50667681 CHEMBL6188370

SMILES CN1CC2(CCN(c3nc(Nc4cn(C(F)F)cn4)cnc3C#N)C2)C1

InChI Key InChIKey=AUBVSRLWPUGPKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50667681   

TargetSerine/threonine-protein kinase Chk1(Human)
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Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667681BDBM50667681(CHEMBL6188370)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST-fused human full length CHK1 (1 to 476 residues) expressed in baculovirus-infected Sf21 cells using STK1 S1 as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed