BDBM50667579 CHEMBL6189226

SMILES CO[C@H]1C[C@](c2cccc(-n3cc(C(F)(F)F)c4cc(CNC5(C)CCC5)[nH]c4c3=O)c2)(c2nncn2C)C1

InChI Key InChIKey=ZKOQELBAEKKDEM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50667579   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667579BDBM50667579(CHEMBL6189226)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to Cbl-b (unknown origin) assessed as inhibition constant incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed