BDBM50667157 CHEMBL6176080

SMILES CC(C)CNCc1cc(Cl)c2c(c1)C(=O)N(c1cccc([C@H](c3nncn3C)[C@H]3C[C@@H](CC#N)C3)c1)C2

InChI Key InChIKey=YWFRQOOBOXPCET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50667157   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667157BDBM50667157(CHEMBL6176080)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of biotin-tagged Cbl-B (unknown origin) pre-incubated with compound for 60 min followed by Lck addition and measured after 90 mins in pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed