BDBM50666785 CHEMBL6177821

SMILES Cc1ccc([C@H](NC2=NS(=O)(=O)N=C2Nc2cccc(C(=O)N(C)C)c2O)C(C)(C)C)o1

InChI Key InChIKey=FJTSRDJNSPTGCT-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50666785   

TargetC-C chemokine receptor type 7(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666785BDBM50666785(CHEMBL6177821)
Affinity DataKi:  6.5nMAssay Description:Displacement of Mz437 from CCR7 in live HEK293T cells expressing CCR7_GSSG_Nluc assessed as inhibition constant using furimazine as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666785BDBM50666785(CHEMBL6177821)
Affinity DataKi:  9.90nMAssay Description:Displacement of Mz437 from CCR7 (unknown origin) extracted from HEK293T cell membrane harbouring CCR7_GSSG_Nluc assessed as inhibition constant using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-C chemokine receptor type 7(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666785BDBM50666785(CHEMBL6177821)
Affinity DataIC50: 2.94E+4nMAssay Description:Antagonist activity at human CCR7 expressed in HEK293T cells assessed as inhibition of CCL19 mediated Galpha-o activation using Nano-glo nanolucifera...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed