BDBM50666700 CHEMBL6173540

SMILES COc1ccc(N2NC(=O)C(=Cc3cc(Br)cc([N+](=O)[O-])c3)C2=O)cc1

InChI Key InChIKey=SJLASDZOGQMHBW-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50666700   

TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666700BDBM50666700(CHEMBL6173540)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of recombinant hexahistidine-tagged ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) using (5'FAM-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666700BDBM50666700(CHEMBL6173540)
Affinity DataKd:  5.99E+3nMAssay Description:Binding affinity to recombinant hexahistidine-tagged wild type ALKBH5 (66 to 292 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666700BDBM50666700(CHEMBL6173540)
Affinity DataIC50: 3.19E+4nMAssay Description:Inhibition of ALKBH3 (unknown origin) using (5'-FAM-d(CAT)r(GGACm1A)d(TATGT)-3'BHQ1) as substrate preincubated with compound followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666700BDBM50666700(CHEMBL6173540)
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of FTO (31 to 505 residues) (unknown origin) using (5'FAM-d(CAT)r(GGm6ACA)d(TATGT)-3'BHQ1) as substrate preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed