BDBM50666062 CHEMBL6175415

SMILES COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OO)c3)cn(Cc3ccc(C(=O)NO)cc3)c2c1

InChI Key InChIKey=RXSBPIFCCGAVSB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50666062   

TargetHistone deacetylase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666062BDBM50666062(CHEMBL6175415)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666062BDBM50666062(CHEMBL6175415)
Affinity DataIC50: 573nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate incubated for 1 hr by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666062BDBM50666062(CHEMBL6175415)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human recombinant HDAC2 extracted from baculovirus infected Sf9 insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed