BDBM50666034 CHEMBL6160558

SMILES CO[C@H]1C[C@@H](N[C@H]2CCc3ccc(-c4cnc5[nH]nc(-c6ccc(-c7ncccc7C)cc6)c5c4)cc3CC2)C1

InChI Key InChIKey=DUFMTIRRQQHZLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50666034   

TargetTyrosine-protein kinase receptor UFO(Human)
Arcus Biosciences, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666034BDBM50666034(CHEMBL6160558)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human AXL measured after 150 mins by ATP-competitive HTRF based biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Arcus Biosciences, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666034BDBM50666034(CHEMBL6160558)
Affinity DataIC50: 310nMAssay Description:Inhibition of autophosphorylation AXL (unknown origin) expressed in HEK293 cells assessed as NanoLuc activity associated with phosphorylated proteins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed