BDBM50666031 CHEMBL6164490

SMILES FC(F)(F)c1cccnc1-c1ccc(-c2n[nH]c3ncc(-c4ccc5c(c4)CC[C@@H](N4C6COCC4C6)CC5)cc23)cc1

InChI Key InChIKey=SHLQIMYAVAQDBG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50666031   

TargetTyrosine-protein kinase receptor UFO(Human)
Arcus Biosciences, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666031BDBM50666031(CHEMBL6164490)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human AXL measured after 150 mins by ATP-competitive HTRF based biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Arcus Biosciences, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666031BDBM50666031(CHEMBL6164490)
Affinity DataIC50: 730nMAssay Description:Inhibition of autophosphorylation AXL (unknown origin) expressed in HEK293 cells assessed as NanoLuc activity associated with phosphorylated proteins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed