BDBM50666008 CHEMBL6177222

SMILES O=C1OCCN1c1ccc(-c2n[nH]c3ncc(-c4ccc5c(c4)CC[C@@H](N4C6COCC4C6)CC5)cc23)cc1

InChI Key InChIKey=LQEZRSMYNRIYIH-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50666008   

TargetTyrosine-protein kinase receptor UFO(Human)
Arcus Biosciences, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666008BDBM50666008(CHEMBL6177222)
Affinity DataIC50: 15nMAssay Description:Inhibition of human AXL measured after 150 mins by ATP-competitive HTRF based biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Arcus Biosciences, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666008BDBM50666008(CHEMBL6177222)
Affinity DataKd:  27nMAssay Description:Binding affinity to AXL (unknown origin) expressed in HEK293 cells transfected with Nano-Luc fusion vector assessed as dissociation constant by measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Arcus Biosciences, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666008BDBM50666008(CHEMBL6177222)
Affinity DataIC50: 390nMAssay Description:Inhibition of autophosphorylation AXL (unknown origin) expressed in HEK293 cells assessed as NanoLuc activity associated with phosphorylated proteins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed